Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-45427

Single-particle
3.33 Å
EMD-45427
3D View Gallery
Deposition: 19/06/2024
Map released: 25/12/2024
Last modified: 05/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-45427
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9cbn summary report (pdf.gz) Map and 9cbn FULL report (pdf.gz)
EMICSS annotations (xml)

HAstV1 spike in complex with neutralizing Fabs 3H4 and 3B4

EMD-45427

Single-particle
3.33 Å
EMD-45427
3D View Gallery
Deposition: 19/06/2024
Map released: 25/12/2024
Last modified: 05/03/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Human astrovirus 1
Sample: Human astrovirus 1 spike in complex with Fab 3B4 and Fab 3H4
Fitted models: 9cbn

Deposition Authors: Lanning S , DuBois RM , Balasco Serrao VH
Discovery of three novel neutralizing antibody epitopes on the human astrovirus capsid spike and mechanistic insights into virus neutralization.
Lanning S , Aguilar-Hernandez N, Serrao VHB , Lopez T, O'Rourke SM, Lentz A , Ricemeyer L , Espinosa R, Lopez S , Arias CF , DuBois RM
(2025) J Virol , 99 , e0161924 - e0161924
PUBMED: 39846739
DOI: doi:10.1128/jvi.01619-24
ISSN: 1098-5514
ASTM: JOVIAM