Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-44671

Single-particle
3.9 Å
EMD-44671
3D View Gallery
Deposition: 30/04/2024
Map released: 04/09/2024
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44671
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9bln summary report (pdf.gz) Map and 9bln FULL report (pdf.gz)
EMICSS annotations (xml)

The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex

EMD-44671

Single-particle
3.9 Å
EMD-44671
3D View Gallery
Deposition: 30/04/2024
Map released: 04/09/2024
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Pdcd4-40S-eIF4A-eIF3-eIF1 complex
Fitted models: 9bln

Deposition Authors: Brito Querido J , Sokabe M , Diaz-Lopez I , Gordiyenko Y, Zuber P, Yifei D, Albacete-Albacete L, Ramakrishnan V , S Fraser C
Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Brito Querido J , Sokabe M , Diaz-Lopez I , Gordiyenko Y, Zuber P, Du Y , Albacete-Albacete L, Ramakrishnan V , Fraser CS
(2024) Nat Commun , 15 , 6633 - 6633
PUBMED: 39117603
DOI: doi:10.1038/s41467-024-50672-8
ISSN: 2041-1723
Grant Support: