Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!
EMD-44380
Prefusion F glycoprotein ectodomain of Nipah virus ectodomain in complex with DS90 nanobody
EMD-44380
Single-particle3.66 Å
Deposition: 01/04/2024Map released: 04/06/2025
Last modified: 24/12/2025
Sample Organism:
Henipavirus nipahense,
Vicugna pacos
Sample: Prefusion F glycoprotein ectodomain of Nipah virus ectodomain in complex with DS90 nanobody
Fitted models: 9b9e
Deposition Authors: Low YS
,
Isaacs A ,
Modhiran N ,
Watterson D
Sample: Prefusion F glycoprotein ectodomain of Nipah virus ectodomain in complex with DS90 nanobody
Fitted models: 9b9e
Deposition Authors: Low YS
,
Isaacs A ,
Modhiran N ,
Watterson D
A nanobody-based therapeutic targeting Nipah virus limits viral escape.
Isaacs A ,
Nieto GV ,
Zhang X,
Modhiran N ,
Barr J ,
Thakur N,
Low YS ,
Parry RH ,
Barnes JB,
Jara R,
Himelreichs J,
Yao Y ,
Deride C,
Barthou-Gatica B,
Salinas-Rebolledo C,
Ehrenfeld P,
Hen JJ,
Hayes N ,
Paramitha D,
Morgan MS ,
McMillan CLD,
Jones ML ,
Munro TP,
Khromykh AA,
Reading PC ,
Young PR,
Chappell KJ ,
Shi Y ,
Bailey D ,
Marsh GA ,
Chiu S ,
Rojas-Fernandez A ,
Watterson D
(2025) Nat Struct Mol Biol , 32 , 1920 - 1931
,
Nieto GV ,
Zhang X,
Modhiran N ,
Barr J ,
Thakur N,
Low YS ,
Parry RH ,
Barnes JB,
Jara R,
Himelreichs J,
Yao Y ,
Deride C,
Barthou-Gatica B,
Salinas-Rebolledo C,
Ehrenfeld P,
Hen JJ,
Hayes N ,
Paramitha D,
Morgan MS ,
McMillan CLD,
Jones ML ,
Munro TP,
Khromykh AA,
Reading PC ,
Young PR,
Chappell KJ ,
Shi Y ,
Bailey D ,
Marsh GA ,
Chiu S ,
Rojas-Fernandez A ,
Watterson D
(2025) Nat Struct Mol Biol , 32 , 1920 - 1931
Grant Support: