EMD-44161

Single-particle
3.0 Å
EMD-44161
3D View Gallery
Deposition: 20/03/2024
Map released: 12/02/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44161

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-9b3z summary report (pdf.gz) Map-9b3z FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Rat TRPV2 E724A/D725A bound to probenecid and 2-APB

EMD-44161

Single-particle
3.0 Å
EMD-44161
3D View Gallery
Deposition: 20/03/2024
Map released: 12/02/2025
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus norvegicus
Sample: Homotetramer of rat TRPV2 E724A/D725A mutant
Fitted models: 9b3z

Deposition Authors: Pumroy RA , Rocereta JA, Moiseenkova-Bell VY
Structural insights into TRPV2 modulation by probenecid.
Rocereta JA, Sturhahn T, Pumroy RA , Fricke TC , Herzog C, Leffler A , Moiseenkova-Bell V
(2025) Nat Struct Mol Biol , 32 , 1019 - 1029
PUBMED: 39972168
DOI: doi:10.1038/s41594-025-01494-9
ISSN: 1545-9985