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EMD-44130
Open state of kainate receptor GluK2 in complex with agonist glutamate and positive allosteric modulator BPAM344 bound to one concanavalin A dimer. Composite map.
EMD-44130
Composite mapSingle-particle
6.66 Å
Deposition: 18/03/2024Map released: 22/05/2024
Last modified: 13/11/2024
Sample Organism:
Rattus norvegicus,
Canavalia ensiformis
Sample: full-length rat GluK2 tetramer in complex with one concanavalin A homodimer
Fitted models: 9b37
Deposition Authors: Nadezhdin KD
,
Gangwar SP
,
Sobolevsky AI
Sample: full-length rat GluK2 tetramer in complex with one concanavalin A homodimer
Fitted models: 9b37
Deposition Authors: Nadezhdin KD
,
Gangwar SP
,
Sobolevsky AI
Kainate receptor channel opening and gating mechanism.
Gangwar SP
,
Yelshanskaya MV,
Nadezhdin KD
,
Yen LY,
Newton TP
,
Aktolun M
,
Kurnikova MG
,
Sobolevsky AI
(2024) Nature , 630 , 762 - 768
,
Yelshanskaya MV,
Nadezhdin KD
,
Yen LY,
Newton TP
,
Aktolun M
,
Kurnikova MG
,
Sobolevsky AI
(2024) Nature , 630 , 762 - 768
Grant Support:
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS083660 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): R01 NS107253 (United States)
- National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIH/NIAMS): R01 AR078814 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): R01 CA206573 (United States)
