EMD-44069

Single-particle
2.89 Å
EMD-44069
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Deposition: 13/03/2024
Map released: 12/02/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-44069
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9b16 summary report (pdf.gz) Map and 9b16 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human uMtCK1 in complex with ADP and covalent inhibitor CKi

EMD-44069

Single-particle
2.89 Å
EMD-44069
3D View Gallery
Deposition: 13/03/2024
Map released: 12/02/2025
Last modified: 16/04/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Octameric u-type mitochondrial creatine kinase
Fitted models: 9b16

Deposition Authors: Demir M , Koepping L, Zhao J, Sergienko E
Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor.
Demir M , Koepping L, Li Y, Fujimoto L, Bobkov A, Zhao J, Hitosugi T, Sergienko E
(2025) Structure , 33 , 786 - 797.e3
PUBMED: 39904336
DOI: doi:10.1016/j.str.2025.01.008
ISSN: 0969-2126
ASTM: STRUE6