EMD-43802

Single-particle
3.21 Å
EMD-43802
3D View Gallery
Deposition: 24/02/2024
Map released: 02/04/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43802
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9as2 summary report (pdf.gz) Map and 9as2 FULL report (pdf.gz)
EMICSS annotations (xml)

Global reconstruction of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)

EMD-43802

Single-particle
3.21 Å
EMD-43802
3D View Gallery
Deposition: 24/02/2024
Map released: 02/04/2025
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: 5-HT2AR in complex with mini-Gq
Fitted models: 9as2

Deposition Authors: Gumpper RH , Fay JF , Roth BL
The structural diversity of psychedelic drug actions revealed.
Gumpper RH , Jain MK , Kim K, Sun R, Sun N, Xu Z, DiBerto JF, Krumm BE , Kapolka NJ, Kaniskan HU , Nichols DE, Jin J , Fay JF , Roth BL
(2025) Nat Commun , 16 , 2734 - 2734
PUBMED: 40108183
DOI: doi:10.1038/s41467-025-57956-7
ISSN: 2041-1723