EMD-43440

Single-particle
2.67 Å
EMD-43440
3D View Gallery
Deposition: 18/01/2024
Map released: 06/11/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43440

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8vqe summary report (pdf.gz) Map-8vqe FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Homodimeric structure of HER2 S310F extracellular region

EMD-43440

Single-particle
2.67 Å
EMD-43440
3D View Gallery
Deposition: 18/01/2024
Map released: 06/11/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Homodimeric structure of Her2 S310F fused to Fc domain
Fitted models: 8vqe

Deposition Authors: Bang I , Koide S
Selective targeting of oncogenic hotspot mutations of the HER2 extracellular domain.
Bang I , Hattori T , Leloup N, Corrado A , Nyamaa A, Koide A , Geles K , Buck E, Koide S
(2025) Nat Chem Biol , 21 , 706 - 715
PUBMED: 39438724
DOI: doi:10.1038/s41589-024-01751-w
ISSN: 1552-4469
Grant Support: