EMD-43237

Single-particle
3.6 Å
EMD-43237
3D View Gallery
Deposition: 01/01/2024
Map released: 12/02/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43237
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8vhg summary report (pdf.gz) Map and 8vhg FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of the BMAL1/HIF2A heterodimer in Complex with DNA

EMD-43237

Single-particle
3.6 Å
EMD-43237
3D View Gallery
Deposition: 01/01/2024
Map released: 12/02/2025
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus
Sample: Ternary complex of the BMAL1/HIF2A heterodimer bound with DNA
Fitted models: 8vhg

Deposition Authors: Li T , Tsai KL
BMAL1-HIF2A heterodimer modulates circadian variations of myocardial injury.
Ruan W , Li T , Bang IH , Lee J , Deng W, Ma X , Luo C , Du F , Yoo SH , Kim B , Li J , Yuan X , Figarella K , An YA, Wang YY, Liang Y , DeBerge M, Zhang D, Zhou Z , Wang Y, Gorham JM , Seidman JG , Seidman CE , Aranki SF, Nair R, Li L , Narula J, Zhao Z , Gorfe AA , Muehlschlegel JD, Tsai KL , Eltzschig HK
(2025) Nature , 641 , 1017 - 1028
PUBMED: 40269168
DOI: doi:10.1038/s41586-025-08898-z
ISSN: 1476-4687
ASTM: NATUAS