EMD-43228
VRC01 Fab bound to the HIV-1 CH848 DE3 SOSIP
EMD-43228
Single-particle3.9 Å
Deposition: 29/12/2023Map released: 02/10/2024
Last modified: 13/11/2024
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: Antibody Fab bound HIV-1 ectodomain
Fitted models: 8vgw
Deposition Authors: Henderson R
,
Acharya P
Sample: Antibody Fab bound HIV-1 ectodomain
Fitted models: 8vgw
Deposition Authors: Henderson R
,
Acharya P
Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies.
Henderson R ,
Anasti K,
Manne K,
Stalls V ,
Saunders C ,
Bililign Y ,
Williams A,
Bubphamala P,
Montani M,
Kachhap S,
Li J,
Jaing C,
Newman A,
Cain DW,
Lu X,
Venkatayogi S,
Berry M,
Wagh K ,
Korber B ,
Saunders KO ,
Tian M,
Alt F ,
Wiehe K,
Acharya P ,
Alam SM,
Haynes BF
(2024) Nat Commun , 15 , 9503 - 9503
,
Anasti K,
Manne K,
Stalls V ,
Saunders C ,
Bililign Y ,
Williams A,
Bubphamala P,
Montani M,
Kachhap S,
Li J,
Jaing C,
Newman A,
Cain DW,
Lu X,
Venkatayogi S,
Berry M,
Wagh K ,
Korber B ,
Saunders KO ,
Tian M,
Alt F ,
Wiehe K,
Acharya P ,
Alam SM,
Haynes BF
(2024) Nat Commun , 15 , 9503 - 9503
Grant Support:
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): DP2-AI164323 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): UM1AI144371 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): R01AI145687 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U54AI170752 (United States)