EMD-43166

Single-particle
4.1 Å
EMD-43166
3D View Gallery
Deposition: 18/12/2023
Map released: 05/06/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43166

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ve6 summary report (pdf.gz) Map-8ve6 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

(Biarylamine-FT2-WT)1(C10A)3-human transthyretin in the frayed conformation

EMD-43166

Single-particle
4.1 Å
EMD-43166
3D View Gallery
Deposition: 18/12/2023
Map released: 05/06/2024
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Transthyretin
Fitted models: 8ve6

Deposition Authors: Basanta B, Nugroho K , Yan N, Kline GM, Tsai FJ, Wu M, Kelly JW , Lander GC
The conformational landscape of human transthyretin revealed by cryo-EM.
Basanta B, Nugroho K , Yan NL, Kline GM, Powers ET , Tsai FJ, Wu M, Hansel-Harris A , Chen JS, Forli S , Kelly JW , Lander GC
(2025) Nat Struct Mol Biol , 32 , 876 - 883
PUBMED: 39843982
DOI: doi:10.1038/s41594-024-01472-7
ISSN: 1545-9985