EMD-43048

Single-particle
3.12 Å
EMD-43048
3D View Gallery
Deposition: 07/12/2023
Map released: 18/12/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-43048
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v93 summary report (pdf.gz) Map and 8v93 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of E. coli FimH lectin domain bound to Fabs 329-2 and 454-3

EMD-43048

Single-particle
3.12 Å
EMD-43048
3D View Gallery
Deposition: 07/12/2023
Map released: 18/12/2024
Last modified: 04/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Mus musculus, Escherichia coli
Sample: Ternary complex of E. coli FimH with Fabs 329-2 and 454-3
Fitted models: 8v93

Deposition Authors: Lees JA , Han S
Structure-based design of an immunogenic, conformationally stabilized FimH antigen for a urinary tract infection vaccine.
Silmon de Monerri NC , Che Y, Lees JA , Jasti J, Wu H, Griffor MC, Kodali S, Hawkins JC, Lypowy J, Ponce C, Curley K, Esadze A, Carcamo J, McLellan T, Keeney D, Illenberger A, Matsuka YV, Shanker S, Chorro L, Gribenko AV, Han S, Anderson AS, Donald RGK
(2025) PLoS Pathog , 21 , e1012325 - e1012325
PUBMED: 39970181
DOI: doi:10.1371/journal.ppat.1012325
ISSN: 1553-7374
Grant Support: