EMD-42996

Single-particle
3.63 Å
EMD-42996
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42996
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8v6m summary report (pdf.gz) Map and 8v6m FULL report (pdf.gz)
EMICSS annotations (xml)

Inactivated-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs

EMD-42996

Single-particle
3.63 Å
EMD-42996
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 16/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: full-length human TRPV3 in complex with THCV
Fitted models: 8v6m

Deposition Authors: Nadezhdin KD , Neuberger A , Sobolevsky AI , Sobolevsky AI
TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Nadezhdin KD , Neuberger A , Khosrof LS , Talyzina IA, Khau J , Yelshanskaya MV , Sobolevsky AI
(2024) Sci Adv , 10 , eadn2453 - eadn2453
PUBMED: 38691614
DOI: doi:10.1126/sciadv.adn2453
ISSN: 2375-2548