EMD-42995

Single-particle
3.68 Å
EMD-42995
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42995

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8v6l summary report (pdf.gz) Map-8v6l FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Open-state cryo-EM structure of human TRPV3 in presence of tetrahydrocannabivarin (THCV) in cNW30 nanodiscs

EMD-42995

Single-particle
3.68 Å
EMD-42995
3D View Gallery
Deposition: 01/12/2023
Map released: 17/04/2024
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: full-length human TRPV3 in complex with THCV
Fitted models: 8v6l

Deposition Authors: Nadezhdin KD , Neuberger A , Sobolevsky AI , Sobolevsky AI
TRPV3 activation by different agonists accompanied by lipid dissociation from the vanilloid site.
Nadezhdin KD , Neuberger A , Khosrof LS , Talyzina IA, Khau J , Yelshanskaya MV , Sobolevsky AI
(2024) Sci Adv , 10 , eadn2453 - eadn2453
PUBMED: 38691614
DOI: doi:10.1126/sciadv.adn2453
ISSN: 2375-2548