EMD-42595
Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
EMD-42595
Single-particle2.34 Å
Deposition: 01/11/2023Map released: 03/07/2024
Last modified: 13/11/2024
Sample Organism:
Measles virus strain Ichinose-B95a,
synthetic construct
Sample: Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
Fitted models: 8uuq
Deposition Authors: Zyla D
,
Saphire EO
Sample: Structure of the Measles virus Fusion protein in the pre-fusion conformation with bound [FIP-HRC]2-PEG11
Fitted models: 8uuq
Deposition Authors: Zyla D
,
Saphire EO
A neutralizing antibody prevents postfusion transition of measles virus fusion protein.
Zyla DS,
Della Marca R ,
Niemeyer G ,
Zipursky G ,
Stearns K ,
Leedale C ,
Sobolik EB ,
Callaway HM ,
Hariharan C ,
Peng W,
Parekh D ,
Marcink TC,
Diaz Avalos R,
Horvat B ,
Mathieu C ,
Snijder J ,
Greninger AL ,
Hastie KM ,
Niewiesk S ,
Moscona A ,
Porotto M ,
Ollmann Saphire E
(2024) Science , 384 , eadm8693 - eadm8693
,
Niemeyer G ,
Zipursky G ,
Stearns K ,
Leedale C ,
Sobolik EB ,
Callaway HM ,
Hariharan C ,
Peng W,
Parekh D ,
Marcink TC,
Diaz Avalos R,
Horvat B ,
Mathieu C ,
Snijder J ,
Greninger AL ,
Hastie KM ,
Niewiesk S ,
Moscona A ,
Porotto M ,
Ollmann Saphire E
(2024) Science , 384 , eadm8693 - eadm8693
Grant Support:
- Swiss National Science Foundation: P2EZP3_195680 (Switzerland)
- Swiss National Science Foundation: P500PB_210992 (Switzerland)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS105699 (United States)
- National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS): NS091263 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): AI176833 (United States)