Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-42591

Single-particle
3.8 Å
EMD-42591
3D View Gallery
Deposition: 01/11/2023
Map released: 29/11/2023
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42591
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uun summary report (pdf.gz) Map and 8uun FULL report (pdf.gz)
EMICSS annotations (xml)

Prototypic SARS-CoV-2 spike (containing V417) in the closed conformation

EMD-42591

Single-particle
3.8 Å
EMD-42591
3D View Gallery
Deposition: 01/11/2023
Map released: 29/11/2023
Last modified: 09/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Severe acute respiratory syndrome coronavirus 2
Sample: Prototypic SARS-CoV-2 spike (containing V417) in the closed conformation
Fitted models: 8uun

Deposition Authors: Geng Q , Liu B , Li F
Lys417 acts as a molecular switch that regulates the conformation of SARS-CoV-2 spike protein.
Geng Q , Wan Y, Hsueh FC , Shang J , Ye G , Bu F, Herbst M, Wilkens R, Liu B , Li F
(2023) eLife , 12
PUBMED: 37991488
DOI: doi:10.7554/eLife.74060
ISSN: 2050-084X