EMD-42463

Helical reconstruction
2.31 Å
EMD-42463
3D View Gallery
Deposition: 23/10/2023
Map released: 04/09/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42463
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8uq7 summary report (pdf.gz) Map and 8uq7 FULL report (pdf.gz)
EMICSS annotations (xml)

Alzheimer's disease PHF complexed with PET ligand MK-6240

EMD-42463

Helical reconstruction
2.31 Å
EMD-42463
3D View Gallery
Deposition: 23/10/2023
Map released: 04/09/2024
Last modified: 23/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Microtubule-associated protein tau
Fitted models: 8uq7

Deposition Authors: Kunach P , Shahmoradian SH , Diamond MI , Rosa-Neto P
Cryo-EM structure of Alzheimer's disease tau filaments with PET ligand MK-6240.
Kunach P , Vaquer-Alicea J , Smith MS, Monistrol J , Hopewell R, Moquin L, Therriault J , Tissot C , Rahmouni N, Massarweh G, Soucy JP, Guiot MC, Shoichet BK , Rosa-Neto P , Diamond MI , Shahmoradian SH
(2024) Nat Commun , 15 , 8497 - 8497
PUBMED: 39353896
DOI: doi:10.1038/s41467-024-52265-x
ISSN: 2041-1723