EMD-42461

Single-particle
3.96 Å
EMD-42461
3D View Gallery
Deposition: 23/10/2023
Map released: 15/11/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42461

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uq5 summary report (pdf.gz) Map-8uq5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of human RyR2-S2808D in the primed state in the presence of Rapamycin

EMD-42461

Single-particle
3.96 Å
EMD-42461
3D View Gallery
Deposition: 23/10/2023
Map released: 15/11/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Complex of RyR2-S2808D
Fitted models: 8uq5

Deposition Authors: Miotto MC , Marks AR
Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders.
Miotto MC , Reiken S, Wronska A , Yuan Q, Dridi H , Liu Y, Weninger G , Tchagou C, Marks AR
(2024) Nat Commun , 15 , 8080 - 8080
PUBMED: 39278969
DOI: doi:10.1038/s41467-024-51791-y
ISSN: 2041-1723