EMD-42350

Helical reconstruction
3.9 Å
EMD-42350
Deposition: 12/10/2023
Map released: 23/10/2024
Obsolete date: 25/02/2026
Last modified: 25/02/2026
Overview

EMD-42350

 This entry has been made obsolete.

Structure of amplified aSyn filament by using seed amplification assay (SAA) from MSA patient CSF.

EMD-42350

Helical reconstruction
3.9 Å
EMD-42350
Deposition: 12/10/2023
Map released: 23/10/2024
Obsolete date: 25/02/2026
Last modified: 25/02/2026
Sample Organism: Homo sapiens
Sample: Alpha-synuclein protein filament
Fitted models: 8uka

Deposition Authors: Banerjee V, Wang F, Baker ML, Serysheva II, Soto C
Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates.
Wang F, Banerjee V, Barria C, Ramirez S, Allison T, Gorski D, Evans H, Nguyen Q, Harrison D, Al-Lahham R, De Gregorio Carbonell N, Pinho M, Kaalund S, Folke J, Aznar S, Concha-Marambio L, Ishtikhar M, Mallampalli VK, Pritzkow S, Shahnawaz M, Baker ML, Serysheva I, Soto C
(2025) Nat Commun , 16 , 11266 - 11266
PUBMED: 41372188
DOI: doi:10.1038/s41467-025-66146-4
ISSN: 2041-1723