Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-4225

Single-particle
3.07 Å
EMD-4225
3D View Gallery
Deposition: 19/12/2017
Map released: 31/01/2018
Last modified: 01/03/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-4225
Download
3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6fbs summary report (pdf.gz) Map and PDB model 6fuw summary report (pdf.gz) Map and 6fbs FULL report (pdf.gz) Map and 6fuw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human CPSF160-WDR33-CPSF30 complex bound to the PAS AAUAAA motif at 3.1 Angstrom resolution.

EMD-4225

Single-particle
3.07 Å
EMD-4225
3D View Gallery
Deposition: 19/12/2017
Map released: 31/01/2018
Last modified: 01/03/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, unidentified adenovirus
Sample: Human CPSF160-WDR33-CPSF30 heterotrimer bound to the AAUAAA motif of the Polyadenylation Signal
Fitted models: 6fbs, 6fuw

Deposition Authors: Clerici M , Faini M , Jinek M
Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
Clerici M , Faini M , Muckenfuss LM, Aebersold R , Jinek M
(2018) Nat Struct Mol Biol , 25 , 135 - 138
PUBMED: 29358758
DOI: doi:10.1038/s41594-017-0020-6
ISSN: 1545-9985