EMD-42151

Single-particle
3.1 Å
EMD-42151
3D View Gallery
Deposition: 28/09/2023
Map released: 16/10/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42151

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8udr summary report (pdf.gz) Map-8udr FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of the P1B7 antibody bound to the Sotorasib-modified KRas G12C peptide presented by the A*03:01 MHC I complex

EMD-42151

Single-particle
3.1 Å
EMD-42151
3D View Gallery
Deposition: 28/09/2023
Map released: 16/10/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: P1B7 antibody:V7-Sotorasib A*03:01 MHC I complex
Fitted models: 8udr

Deposition Authors: Chan LM , Roweder PJ, Craik CS , Verba KA
Therapeutic Targeting and Structural Characterization of a Sotorasib-Modified KRAS G12C-MHC I Complex Demonstrate the Antitumor Efficacy of Hapten-Based Strategies.
Pandey A , Rohweder PJ , Chan LM , Ongpipattanakul C , Chung DH , Paolella B , Quimby FM , Nguyen N , Verba KA , Evans MJ , Craik CS
(2025) Cancer Res. , 85 , 329 - 341
PUBMED: 39656104
DOI: doi:10.1158/0008-5472.CAN-24-2450
ISSN: 1538-7445
ASTM: CNREA8