EMD-42124

Single-particle
3.0 Å
EMD-42124
3D View Gallery
Deposition: 26/09/2023
Map released: 22/11/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42124
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ucd summary report (pdf.gz) Map and 8ucd FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human STEAP1 in complex with AMG 509 Fab

EMD-42124

Single-particle
3.0 Å
EMD-42124
3D View Gallery
Deposition: 26/09/2023
Map released: 22/11/2023
Last modified: 13/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: complex of human STEAP1 with AMG 509 Fab
Fitted models: 8ucd

Deposition Authors: Li F , Bailis JM
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer.
Nolan-Stevaux O , Li C , Liang L , Zhan J , Estrada J , Osgood T , Li F , Zhang H , Case R , Murawsky CM , Estes B , Moore GL , Bernett MJ , Muchhal U , Desjarlais JR , Staley BK , Stevens J , Cooke KS , Aeffner F , Thomas O , Stieglmaier J , Lee JL , Coxon A , Bailis JM
(2024) Cancer Discov , 14 , 90 - 103
PUBMED: 37861452
DOI: doi:10.1158/2159-8290.CD-23-0984
ISSN: 2159-8290
Grant Support: