EMD-42073

Single-particle
2.97 Å
EMD-42073
3D View Gallery
Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42073

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8uaw summary report (pdf.gz) Map-8uaw FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM Structure of Brucella Abortus Lumazine Synthase (BLS) Engineered with Shiga Toxin II subunit B (Stx2B)

EMD-42073

Single-particle
2.97 Å
EMD-42073
3D View Gallery
Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli O157:H7, Brucella abortus bv. 1 str. 9-941
Sample: Chimeric BLS-Stx2B protein
Fitted models: 8uaw

Deposition Authors: Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Zylberman V, Goldbaum FA, Borgnia MJ, Otero LH
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome.
Cristofalo AE, Sharma A, Cerutti ML, Sharma K, Melero R , Pardo R, Goldbaum FA, Borgnia M, Zylberman V, Otero LH
(2025) Protein Sci , 34 , e70178 - e70178
PUBMED: 40411437
DOI: doi:10.1002/pro.70178
ISSN: 1469-896X
ASTM: PRCIEI