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EMD-42072

Single-particle
2.37 Å
EMD-42072 Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-42072

Cryo-EM Structure of Brucella Abortus Lumazine Synthase (BLS) Engineered with Shiga Toxin I subunit B (Stx1B)

EMD-42072

Single-particle
2.37 Å
EMD-42072 Deposition: 22/09/2023
Map released: 26/03/2025
Last modified: 08/10/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Escherichia coli O157:H7, Brucella abortus biovar 1 (strain 9-941)
Sample: Chimeric BLS-Stx1B protein
Fitted models: 8uav

Deposition Authors: Cristofalo AE , Sharma A , Cerutti ML , Sharma K , Zylberman V , Goldbaum FA , Borgnia MJ , Otero LH
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against hemolytic uremic syndrome.
Cristofalo AE , Sharma A , Cerutti ML , Sharma K , Melero R, Pardo R, Goldbaum FA , Borgnia M, Zylberman V , Otero LH
(2025) Protein Sci , 34 , e70178 - e70178
PUBMED: 40411437
DOI: doi:10.1002/pro.70178
ISSN: 1469-896X
ASTM: PRCIEI