EMD-41837

Single-particle
2.7 Å
EMD-41837
3D View Gallery
Deposition: 04/09/2023
Map released: 17/01/2024
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41837

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8u1x summary report (pdf.gz) Map-8u1x FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The structure of the PP2A-B56Delta holoenzyme mutant - E197K

EMD-41837

Single-particle
2.7 Å
EMD-41837
3D View Gallery
Deposition: 04/09/2023
Map released: 17/01/2024
Last modified: 17/01/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Protein Phosphatase 2A B56 Delta holoenzyme mutant - E197K
Fitted models: 8u1x

Deposition Authors: Wu CG , Xing Y
B56 delta long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
Wu CG , Balakrishnan VK, Merrill RA, Parihar PS , Konovolov K, Chen YC, Xu Z , Wei H , Sundaresan R, Cui Q , Wadzinski BE , Swingle MR, Musiyenko A , Chung WK , Honkanen RE , Suzuki A , Huang X , Strack S , Xing Y
(2024) PNAS , 121 , e2310727120 - e2310727120
PUBMED: 38150499
DOI: doi:10.1073/pnas.2310727120
ISSN: 1091-6490
ASTM: PNASA6