EMD-41613

Single-particle
2.96 Å
EMD-41613
3D View Gallery
Deposition: 15/08/2023
Map released: 08/11/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41613
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8ttw summary report (pdf.gz) Map and 8ttw FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074

EMD-41613

Single-particle
2.96 Å
EMD-41613
3D View Gallery
Deposition: 15/08/2023
Map released: 08/11/2023
Last modified: 21/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human immunodeficiency virus 1
Sample: Complex of BG505 SOSIP.664 with temsavir and the antibody Fabs of 8anc195 and 10-1074
Fitted models: 8ttw

Deposition Authors: Tolbert WD , Pozharski E, Pazgier M
Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Prevost J , Chen Y , Zhou F, Tolbert WD , Gasser R , Medjahed H, Nayrac M , Nguyen DN, Gottumukkala S, Hessell AJ , Rao VB , Pozharski E, Huang RK, Matthies D , Finzi A, Pazgier M
(2023) Nat Commun , 14 , 6710 - 6710
PUBMED: 37872202
DOI: doi:10.1038/s41467-023-42500-2
ISSN: 2041-1723