EMD-41581

Single-particle
2.78 Å
EMD-41581
3D View Gallery
Deposition: 09/08/2023
Map released: 14/08/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-41581

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8trj summary report (pdf.gz) Map-8trj FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the rat P2X7 receptor in complex with the high-affinity agonist BzATP

EMD-41581

Single-particle
2.78 Å
EMD-41581
3D View Gallery
Deposition: 09/08/2023
Map released: 14/08/2024
Last modified: 14/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Rattus
Sample: Membrane protein
Fitted models: 8trj

Deposition Authors: Oken AC , Lisi NE, Krishnamurthy I , McCarthy AE, Godsey MH , Glasfeld A , Mansoor SE
High-affinity agonism at the P2X 7 receptor is mediated by three residues outside the orthosteric pocket.
Oken AC , Lisi NE, Krishnamurthy I , McCarthy AE, Godsey MH , Glasfeld A , Mansoor SE
(2024) Nat Commun , 15 , 6662 - 6662
PUBMED: 39107314
DOI: doi:10.1038/s41467-024-50771-6
ISSN: 2041-1723