EMD-41072
Human leukocyte antigen bound by two alloreactive antibody Fabs
EMD-41072
Single-particle3.14 Å
Deposition: 16/06/2023Map released: 25/12/2024
Last modified: 14/01/2026
Sample Organism:
Homo sapiens
Sample: L02/M07/A*01:01 complex
Fitted models: 8t6m
Deposition Authors: Kizziah JL
,
Killian JT ,
Diaz-Avalos R,
Qiu S,
Yang G,
Green T,
Lund FE
Sample: L02/M07/A*01:01 complex
Fitted models: 8t6m
Deposition Authors: Kizziah JL
,
Killian JT ,
Diaz-Avalos R,
Qiu S,
Yang G,
Green T,
Lund FE
Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients.
Killian Jr JT,
King RG,
Lucander ACK,
Kizziah JL ,
Fucile CF,
Diaz-Avalos R,
Qiu S,
Silva-Sanchez A,
Mousseau BJ,
Macon KJ,
Callahan AR,
Yang G,
Hossain ME,
Akther J,
Good DB,
Kelso S,
Houp JA,
Rosenblum F,
Porrett PM,
Ong SC,
Kumar V,
Saphire EO,
Kearney JF,
Randall TD,
Rosenberg AF,
Green TJ,
Lund FE
(2025) Immunity , 58 , 3040 - 3060.e12
,
Fucile CF,
Diaz-Avalos R,
Qiu S,
Silva-Sanchez A,
Mousseau BJ,
Macon KJ,
Callahan AR,
Yang G,
Hossain ME,
Akther J,
Good DB,
Kelso S,
Houp JA,
Rosenblum F,
Porrett PM,
Ong SC,
Kumar V,
Saphire EO,
Kearney JF,
Randall TD,
Rosenberg AF,
Green TJ,
Lund FE
(2025) Immunity , 58 , 3040 - 3060.e12
Grant Support:
- National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Disease (NIH/NIDDK): T32DK007545 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): T32AI007051 (United States)
- National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID): U19AI142737 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): S10OD024978 (United States)
- National Institutes of Health/National Cancer Institute (NIH/NCI): P30CA013148 (United States)