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EMD-40764
Human asparagine synthetase (apo-ASNS)
EMD-40764
Single-particle3.5 Å
Deposition: 12/05/2023Map released: 22/05/2024
Last modified: 05/02/2025
Sample Organism:
Homo sapiens
Sample: human asparagine synthetase dimer form
Fitted models: 8sue
Deposition Authors: Coricello A
,
Zhu W
,
Lupia A
,
Gratteri C
,
Vos M,
Chaptal V
,
Alcaro S
,
Takagi Y
,
Richards N
Sample: human asparagine synthetase dimer form
Fitted models: 8sue
Deposition Authors: Coricello A
,
Zhu W
,
Lupia A
,
Gratteri C
,
Vos M,
Chaptal V
,
Alcaro S
,
Takagi Y
,
Richards N
3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase.
Coricello A
,
Nardone AJ,
Lupia A
,
Gratteri C
,
Vos M,
Chaptal V
,
Alcaro S
,
Zhu W
,
Takagi Y
,
Richards NGJ
(2024) Nat Commun , 15 , 10538 - 10538
,
Nardone AJ,
Lupia A
,
Gratteri C
,
Vos M,
Chaptal V
,
Alcaro S
,
Zhu W
,
Takagi Y
,
Richards NGJ
(2024) Nat Commun , 15 , 10538 - 10538
Grant Support:
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): R01GM111695 (United States)
- National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS): S10OD028723 (United States)
- Centre National de la Recherche Scientifique (CNRS): ANR-19-CE11-0023-01 (France)
- Biotechnology and Biological Sciences Research Council (BBSRC): P/0118017/1 (United Kingdom)
- European Commission: FESR FSE 2014- 2020 (European Union)
