EMD-40716

Single-particle
3.53 Å
EMD-40716
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Deposition: 05/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40716
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8sr0 summary report (pdf.gz) Map and 8sr0 FULL report (pdf.gz)
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CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined

EMD-40716

Single-particle
3.53 Å
EMD-40716
3D View Gallery
Deposition: 05/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: therapeutic antibody (favezelimab) bound to human LAG3
Fitted models: 8sr0

Deposition Authors: Mishra AK , Shahid S, Karade SS, Mariuzza RA
CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Mishra AK , Shahid S, Karade SS, Agnihotri P, Kolesnikov A, Hasan SS, Mariuzza RA
(2023) Structure , 31 , 1149
PUBMED: 37619561
DOI: doi:10.1016/j.str.2023.07.013
ISSN: 0969-2126
ASTM: STRUE6