EMD-40421

Helical reconstruction
3.8 Å
EMD-40421
3D View Gallery
Deposition: 10/04/2023
Map released: 03/04/2024
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40421

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8sel summary report (pdf.gz) Map-8sel FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Type IIIb beta-amyloid 40 Filaments from Down Syndrome

EMD-40421

Helical reconstruction
3.8 Å
EMD-40421
3D View Gallery
Deposition: 10/04/2023
Map released: 03/04/2024
Last modified: 26/06/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Type IIIb beta amyloid 40 from Human trisomy 21 Case 2.
Fitted models: 8sel

Deposition Authors: Hoq MR, Vago FS, Bharath SR, Jiang W
Cryo-EM structures of amyloid-beta and tau filaments in Down syndrome.
Fernandez A, Hoq MR, Hallinan GI, Li D, Bharath SR, Vago FS, Zhang X, Ozcan KA , Newell KL, Garringer HJ , Jiang W , Ghetti B , Vidal R
(2024) Nat Struct Mol Biol , 31 , 903 - 909
PUBMED: 38553642
DOI: doi:10.1038/s41594-024-01252-3
ISSN: 1545-9985