EMD-40407

Single-particle
3.2 Å
EMD-40407 Deposition: 08/04/2023
Map released: 11/10/2023
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40407

Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 2)

EMD-40407

Single-particle
3.2 Å
EMD-40407 Deposition: 08/04/2023
Map released: 11/10/2023
Last modified: 28/05/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Cryo-EM structure of a double loaded human UBA7-UBE2L6-ISG15 thioester mimetic complex (Form 2)
Fitted models: 8se9

Deposition Authors: Afsar M, Jia L, Ruben EA, Olsen SK
Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.
Afsar M, Liu G , Jia L, Ruben EA, Nayak D , Sayyad Z , Bury PDS, Cano KE, Nayak A , Zhao XR, Shukla A, Sung P , Wasmuth EV, Gack MU , Olsen SK
(2023) Nat Commun , 14 , 4786 - 4786
PUBMED: 37553340
DOI: doi:10.1038/s41467-023-39780-z
ISSN: 2041-1723