EMD-40042

Single-particle
2.05 Å
EMD-40042
3D View Gallery
Deposition: 09/03/2023
Map released: 09/08/2023
Last modified: 11/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-40042

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ghe summary report (pdf.gz) Map-8ghe FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

The structure of h12-LOX in tetrameric form bound to endogenous inhibitor oleoyl-CoA

EMD-40042

Single-particle
2.05 Å
EMD-40042
3D View Gallery
Deposition: 09/03/2023
Map released: 09/08/2023
Last modified: 11/10/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Tetrameric human 12-Lipoxygenase bound to endogenous inhibitor oleoyl-CoA
Fitted models: 8ghe

Deposition Authors: Black KA , Mobbs JI , Venugopal H , Thal DM , Glukhova A
Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.
Mobbs JI , Black KA , Tran M , Burger WAC , Venugopal H , Holman TR , Holinstat M , Thal DM , Glukhova A
(2023) Blood , 142 , 1233 - 1242
PUBMED: 37506345
DOI: doi:10.1182/blood.2023020441
ISSN: 1528-0020