EMD-39553

Single-particle
2.93 Å
EMD-39553
3D View Gallery
Deposition: 22/03/2024
Map released: 25/06/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39553

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8yry summary report (pdf.gz) Map-8yry FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

HER3 in complex with FAb Hu3f8

EMD-39553

Single-particle
2.93 Å
EMD-39553
3D View Gallery
Deposition: 22/03/2024
Map released: 25/06/2025
Last modified: 07/01/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: complex of Her3 with fab Hu3f8
Fitted models: 8yry

Deposition Authors: Wang M, Li X
DB-1310, a HER3-targeting antibody-drug conjugate, has synergistic anti-tumor activity with trastuzumab in HER2- and HER3-expressing breast cancer.
Li X , Liang L, Zhu Z, Hua H, Qiu Y
(2025) Cancer Biol Med , 22 , 231 - 236
PUBMED: 40110648
DOI: doi:10.20892/j.issn.2095-3941.2024.0586
ISSN: 2095-3941
Grant Support: