EMD-39542

Single-particle
3.14 Å
EMD-39542
3D View Gallery
Deposition: 21/03/2024
Map released: 22/05/2024
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-39542
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8yrg summary report (pdf.gz) Map and 8yrg FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of fospropofol-bound MRGPRX4-Gq complex

EMD-39542

Single-particle
3.14 Å
EMD-39542
3D View Gallery
Deposition: 21/03/2024
Map released: 22/05/2024
Last modified: 18/06/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: fospropofol-bound MRGPRX4-Gq complex
Fitted models: 8yrg

Deposition Authors: Cao C , Fay JF , Roth BL
MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model.
Chien DC , Limjunyawong N , Cao C , Meixiong J , Peng Q, Ho CY , Fay JF , Roth BL , Dong X
(2024) Sci Transl Med , 16 , eadk8198 - eadk8198
PUBMED: 38718132
DOI: doi:10.1126/scitranslmed.adk8198
ISSN: 1946-6242