EMD-38223

Single-particle
3.0 Å
EMD-38223
3D View Gallery
Deposition: 06/12/2023
Map released: 11/06/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-38223

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8xbm summary report (pdf.gz) Map-8xbm FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Structure of Cx43/GJA1 gap junction intercellular channel in complex with diC8-PIP2

EMD-38223

Single-particle
3.0 Å
EMD-38223
3D View Gallery
Deposition: 06/12/2023
Map released: 11/06/2025
Last modified: 25/02/2026
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: Dodecameric complex of human Cx43-M257 in lipid nanodiscs (POPE) in the presence of diC8-PIP2 (16-fold molar excess)
Fitted models: 8xbm

Deposition Authors: Lee HJ , Oh JS , Cha HJ , Lee CW , Jang HS , Woo JS

PIP2-dependent conformational changes and stabilization of cytoplasmic loop in Cx43/GJA1 gap junction channel
Lee HJ , Cha HJ , Woo JS
To Be Published