EMD-37947
Cryo-EM structure of prefusion-stabilized RSV F (DS-Cav1 sc9-10 strain: B18537) in complex with humanized nAb 5B11
EMD-37947
Single-particle3.51 Å
Deposition: 01/11/2023Map released: 13/11/2024
Last modified: 04/06/2025
Sample Organism:
Mus musculus,
Human respiratory syncytial virus B
Sample: RSV B18537 preF in complex with humanized mAb 5B11
Fitted models: 8wz5
Deposition Authors: Liu L, Sun H, Sun Y, Zheng Q
,
Li S ,
Zheng Z ,
Xia N ,
Xia N
Sample: RSV B18537 preF in complex with humanized mAb 5B11
Fitted models: 8wz5
Deposition Authors: Liu L, Sun H, Sun Y, Zheng Q
,
Li S ,
Zheng Z ,
Xia N ,
Xia N
A potent broad-spectrum neutralizing antibody targeting a conserved region of the prefusion RSV F protein.
Sun Y,
Liu L,
Qiang H,
Sun H,
Jiang Y ,
Ren L,
Jiang Z,
Lei S,
Chen L,
Wang Y,
Lin X,
Wang G,
Huang Y,
Fu Y,
Shi Y,
Chen X,
Yu H,
Li S ,
Luo W ,
Liu E,
Zheng Q ,
Zheng Z ,
Xia N
(2024) Nat Commun , 15 , 10085 - 10085
,
Ren L,
Jiang Z,
Lei S,
Chen L,
Wang Y,
Lin X,
Wang G,
Huang Y,
Fu Y,
Shi Y,
Chen X,
Yu H,
Li S ,
Luo W ,
Liu E,
Zheng Q ,
Zheng Z ,
Xia N
(2024) Nat Commun , 15 , 10085 - 10085
Grant Support:
- Not funded: (China)