EMD-37505
Cryo-EM structures of peptide free and Gs-coupled GCGR
EMD-37505
Single-particle2.71 Å
Deposition: 20/09/2023Map released: 06/03/2024
Last modified: 23/07/2025
Sample Organism:
Homo sapiens,
Rattus norvegicus,
Bos taurus,
synthetic construct,
Spodoptera frugiperda
Sample: Cryo-EM structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and G protein
Fitted models: 8wg8
Deposition Authors: Cong ZT, Zhao FH, Li Y, Luo G
,
Zhou QT,
Yang DH,
Wang MW
Sample: Cryo-EM structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and G protein
Fitted models: 8wg8
Deposition Authors: Cong ZT, Zhao FH, Li Y, Luo G
,
Zhou QT,
Yang DH,
Wang MW
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins.
Cong Z,
Zhao F,
Li Y,
Luo G ,
Mai Y,
Chen X,
Chen Y,
Lin S,
Cai X,
Zhou Q ,
Yang D ,
Wang MW
(2024) Cell Discov , 10 , 18 - 18
,
Mai Y,
Chen X,
Chen Y,
Lin S,
Cai X,
Zhou Q ,
Yang D ,
Wang MW
(2024) Cell Discov , 10 , 18 - 18
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 32071203 (China)
- National Natural Science Foundation of China (NSFC): 81922071 (China)
- National Natural Science Foundation of China (NSFC): 81773792 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)