EMD-37504

Single-particle
2.54 Å
EMD-37504
3D View Gallery
Deposition: 20/09/2023
Map released: 06/03/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37504

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8wg7 summary report (pdf.gz) Map-8wg7 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structures of peptide free and Gs-coupled GLP-1R

EMD-37504

Single-particle
2.54 Å
EMD-37504
3D View Gallery
Deposition: 20/09/2023
Map released: 06/03/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, synthetic construct
Sample: Cryo-EM structure of the human glucagon like peptide 1 receptor in complex with tirzepatide and G protein
Fitted models: 8wg7

Deposition Authors: Cong ZT, Zhao FH, Li Y, Luo G, Zhou QT, Yang DH, Wang MW
Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins.
Cong Z, Zhao F, Li Y, Luo G, Mai Y, Chen X, Chen Y, Lin S, Cai X, Zhou Q , Yang D , Wang MW
(2024) Cell Discov , 10 , 18 - 18
PUBMED: 38346960
DOI: doi:10.1038/s41421-024-00649-0
ISSN: 2056-5968