EMD-37432

Single-particle
3.2 Å
EMD-37432
3D View Gallery
Deposition: 11/09/2023
Map released: 27/12/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37432
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8wc6 summary report (pdf.gz) Map and 8wc6 FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the PEA-bound mTAAR1-Gs complex

EMD-37432

Single-particle
3.2 Å
EMD-37432
3D View Gallery
Deposition: 11/09/2023
Map released: 27/12/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct, Mus musculus
Sample: Cryo-EM structure of the PEA-bound mTAAR1-Gs complex
Fitted models: 8wc6

Deposition Authors: Rong NK, Guo LL, Zhang MH, Li Q, Yang F, Sun JP
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L , Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, Yan W, Kong Y, Yang L, Wang X, Lei D, Feng X , Liu X, Yu X, Wang Y, Li Q, Shao ZH, Yang F, Sun JP
(2023) Cell , 186 , 5347 - 5362.e24
PUBMED: 37963465
DOI: doi:10.1016/j.cell.2023.10.014
ISSN: 1097-4172