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EMD-37430
Cryo-EM structure of the ZH8651-bound mTAAR1-Gs complex
EMD-37430
Single-particle3.1 Å
Deposition: 11/09/2023Map released: 27/12/2023
Last modified: 06/11/2024
Sample Organism:
Homo sapiens,
Mus musculus,
synthetic construct
Sample: Cryo-EM structure of the ZH8651-bound mTAAR1-Gs complex
Fitted models: 8wc4
Deposition Authors: Rong NK, Guo LL, Zhang MH, Li Q, Yang F, Sun JP
Sample: Cryo-EM structure of the ZH8651-bound mTAAR1-Gs complex
Fitted models: 8wc4
Deposition Authors: Rong NK, Guo LL, Zhang MH, Li Q, Yang F, Sun JP
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Shang P,
Rong N,
Jiang JJ,
Cheng J,
Zhang MH,
Kang D,
Qi L 
,
Guo L,
Yang GM,
Liu Q,
Zhou Z,
Li XB,
Zhu KK,
Meng QB,
Han X,
Yan W,
Kong Y,
Yang L,
Wang X,
Lei D,
Feng X ,
Liu X,
Yu X,
Wang Y,
Li Q,
Shao ZH,
Yang F,
Sun JP
(2023) Cell , 186 , 5347 - 5362.e24
,
Guo L,
Yang GM,
Liu Q,
Zhou Z,
Li XB,
Zhu KK,
Meng QB,
Han X,
Yan W,
Kong Y,
Yang L,
Wang X,
Lei D,
Feng X ,
Liu X,
Yu X,
Wang Y,
Li Q,
Shao ZH,
Yang F,
Sun JP
(2023) Cell , 186 , 5347 - 5362.e24
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