EMD-37429

Single-particle
3.0 Å
EMD-37429
3D View Gallery
Deposition: 11/09/2023
Map released: 27/12/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37429

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8wc3 summary report (pdf.gz) Map-8wc3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the SEP363856-bound mTAAR1-Gs complex

EMD-37429

Single-particle
3.0 Å
EMD-37429
3D View Gallery
Deposition: 11/09/2023
Map released: 27/12/2023
Last modified: 20/11/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus, synthetic construct
Sample: Cryo-EM structure of the SEP363856-bound mTAAR1-Gs complex
Fitted models: 8wc3

Deposition Authors: Rong NK, Guo LL, Zhang MH, Li Q, Yang F, Sun JP
Structural and signaling mechanisms of TAAR1 enabled preferential agonist design.
Shang P, Rong N, Jiang JJ, Cheng J, Zhang MH, Kang D, Qi L , Guo L, Yang GM, Liu Q, Zhou Z, Li XB, Zhu KK, Meng QB, Han X, Yan W, Kong Y, Yang L, Wang X, Lei D, Feng X , Liu X, Yu X, Wang Y, Li Q, Shao ZH, Yang F, Sun JP
(2023) Cell , 186 , 5347 - 5362.e24
PUBMED: 37963465
DOI: doi:10.1016/j.cell.2023.10.014
ISSN: 1097-4172