EMD-37357
Cryo-EM structure of the AA-14-bound GPR101-Gs complex
EMD-37357
Single-particle3.3 Å
Deposition: 04/09/2023Map released: 03/01/2024
Last modified: 13/11/2024
Sample Organism:
Homo sapiens
Sample: Cryo-EM structure of the AA14-bound GPR101-Gs complex
Fitted models: 8w8r
Deposition Authors: Sun JP
,
Yu X ,
Gao N,
Yang F,
Wang JY,
Yang Z,
Guan Y,
Wang GP
Sample: Cryo-EM structure of the AA14-bound GPR101-Gs complex
Fitted models: 8w8r
Deposition Authors: Sun JP
,
Yu X ,
Gao N,
Yang F,
Wang JY,
Yang Z,
Guan Y,
Wang GP
Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Yang Z,
Wang JY,
Yang F,
Zhu KK,
Wang GP,
Guan Y,
Ning SL,
Lu Y,
Li Y ,
Zhang C,
Zheng Y,
Zhou SH,
Wang XW,
Wang MW,
Xiao P ,
Yi F ,
Zhang C,
Zhang PJ,
Xu F ,
Liu BH ,
Zhang H,
Yu X ,
Gao N,
Sun JP
(2024) Nat Chem Biol , 20 , 484 - 492
,
Zhang C,
Zheng Y,
Zhou SH,
Wang XW,
Wang MW,
Xiao P ,
Yi F ,
Zhang C,
Zhang PJ,
Xu F ,
Liu BH ,
Zhang H,
Yu X ,
Gao N,
Sun JP
(2024) Nat Chem Biol , 20 , 484 - 492
Grant Support:
- National Natural Science Foundation of China (NSFC): 31725007 (China)
- National Natural Science Foundation of China (NSFC): 32130055 (China)
- National Natural Science Foundation of China (NSFC): 92057121 (China)
- National Science Foundation (NSF, China): 81825022 (China)
- National Science Foundation (NSF, China): 82225011 (China)