Happy Holidays and New year from the EMDB! Please be advised that the EMDB team will be operating at reduced capacity between December 15th - January 12th. With this in mind we would ask that you be prepared for longer reply times through both our helpdesk system and the OneDep deposition system. well done on a productive 2025, wishing you all the best and we will see you in 2026!

EMD-37270

Single-particle
3.3 Å
EMD-37270
3D View Gallery
Deposition: 25/08/2023
Map released: 13/12/2023
Last modified: 13/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37270
Download
3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8w4u summary report (pdf.gz) Map and 8w4u FULL report (pdf.gz)
EMICSS annotations (xml)

human KCNQ2-CaM in complex with PIP2 and HN37

EMD-37270

Single-particle
3.3 Å
EMD-37270
3D View Gallery
Deposition: 25/08/2023
Map released: 13/12/2023
Last modified: 13/12/2023
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human KCNQ2-CaM in complex with PIP2 and HN37
Fitted models: 8w4u

Deposition Authors: Ma D , Li X, Guo J
Ligand activation mechanisms of human KCNQ2 channel.
Ma D , Zheng Y, Li X, Zhou X, Yang Z, Zhang Y, Wang L , Zhang W, Fang J, Zhao G, Hou P, Nan F, Yang W , Su N , Gao Z , Guo J
(2023) Nat Commun , 14 , 6632 - 6632
PUBMED: 37857637
DOI: doi:10.1038/s41467-023-42416-x
ISSN: 2041-1723