EMD-37251

Single-particle
2.89 Å
EMD-37251
3D View Gallery
Deposition: 22/08/2023
Map released: 01/05/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37251

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8ki3 summary report (pdf.gz) Map-8ki3 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Structure of the human ATP synthase bound to bedaquiline (composite)

EMD-37251

Single-particle
2.89 Å
EMD-37251
3D View Gallery
Deposition: 22/08/2023
Map released: 01/05/2024
Last modified: 02/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: human ATP synthase
Fitted models: 8ki3

Deposition Authors: Lai Y, Zhang Y, Gong H
Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Zhang Y, Lai Y, Zhou S, Ran T , Zhang Y, Zhao Z, Feng Z, Yu L, Xu J, Shi K, Wang J, Pang Y, Li L, Chen H, Guddat LW , Gao Y , Liu F , Rao Z, Gong H
(2024) Nature , 631 , 409 - 414
PUBMED: 38961288
DOI: doi:10.1038/s41586-024-07605-8
ISSN: 1476-4687
ASTM: NATUAS