EMD-37210

Single-particle
3.17 Å
EMD-37210
3D View Gallery
Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-37210

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8kg5 summary report (pdf.gz) Map-8kg5 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Prefusion RSV F Bound to Lonafarnib and D25 Fab

EMD-37210

Single-particle
3.17 Å
EMD-37210
3D View Gallery
Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Human respiratory syncytial virus A (strain A2), Enterobacteria phage T4
Sample: Prefusion RSV F Bound to Lonafarnib and D25 Fab
Fitted models: 8kg5

Deposition Authors: Yang Q, Xue B , Liu F , Peng W, Chen X
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Yang Q, Xue B , Liu F , Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F, Zhou Y, Zheng J, Peng W, Shang J , Chen X
(2024) Signal Transduct Target Ther , 9 , 144 - 144
PUBMED: 38853183
DOI: doi:10.1038/s41392-024-01858-5
ISSN: 2059-3635