EMD-36300

Single-particle
2.87 Å
EMD-36300
3D View Gallery
Deposition: 25/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-36300

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8jhy summary report (pdf.gz) Map-8jhy FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

Cryo-EM structure of compound 9n bound ketone body receptor HCAR2-Gi signaling complex

EMD-36300

Single-particle
2.87 Å
EMD-36300
3D View Gallery
Deposition: 25/05/2023
Map released: 06/09/2023
Last modified: 30/10/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, Mus musculus
Sample: HCA2 in complex with Gi heterotrimer
Fitted models: 8jhy

Deposition Authors: Zhao C , Tian XW, Liu Y, Cheng L, Yan W, Shao ZH
Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.
Zhao C , Wang H, Liu Y, Cheng L, Wang B, Tian X, Fu H, Wu C, Li Z, Shen C, Yu J, Yang S, Hu H, Fu P, Ma L , Wang C, Yan W, Shao Z
(2023) Mol Cell , 83 , 3171
PUBMED: 37597514
DOI: doi:10.1016/j.molcel.2023.07.030
ISSN: 1097-2765
ASTM: MOCEFL