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EMD-36012
Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
EMD-36012
Single-particle2.76 Å
Deposition: 26/04/2023Map released: 06/12/2023
Last modified: 16/07/2025
Sample Organism:
Homo sapiens,
synthetic construct
Sample: Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
Fitted models: 8j6r
Deposition Authors: Mao C
,
Gao M,
Zang S,
Zhu Y,
Ma X ,
Zhang Y
Sample: Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
Fitted models: 8j6r
Deposition Authors: Mao C
,
Gao M,
Zang S,
Zhu Y,
Ma X ,
Zhang Y
Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Mao C ,
Gao M,
Zang SK,
Zhu Y,
Shen DD ,
Chen LN,
Yang L,
Wang Z,
Zhang H ,
Wang WW,
Shen Q ,
Lu Y,
Ma X ,
Zhang Y
(2023) Nat Commun , 14 , 7620 - 7620
,
Gao M,
Zang SK,
Zhu Y,
Shen DD ,
Chen LN,
Yang L,
Wang Z,
Zhang H ,
Wang WW,
Shen Q ,
Lu Y,
Ma X ,
Zhang Y
(2023) Nat Commun , 14 , 7620 - 7620
Grant Support: