EMD-36012

Single-particle
2.76 Å
EMD-36012
3D View Gallery
Deposition: 26/04/2023
Map released: 06/12/2023
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-36012

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-8j6r summary report (pdf.gz) Map-8j6r FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex

EMD-36012

Single-particle
2.76 Å
EMD-36012
3D View Gallery
Deposition: 26/04/2023
Map released: 06/12/2023
Last modified: 16/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens, synthetic construct
Sample: Cryo-EM structure of the MK-6892-bound human HCAR2-Gi1 complex
Fitted models: 8j6r

Deposition Authors: Mao C , Gao M, Zang S, Zhu Y, Ma X , Zhang Y
Orthosteric and allosteric modulation of human HCAR2 signaling complex.
Mao C , Gao M, Zang SK, Zhu Y, Shen DD , Chen LN, Yang L, Wang Z, Zhang H , Wang WW, Shen Q , Lu Y, Ma X , Zhang Y
(2023) Nat Commun , 14 , 7620 - 7620
PUBMED: 37993467
DOI: doi:10.1038/s41467-023-43537-z
ISSN: 2041-1723
Grant Support: