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EMD-35741
Cryo-EM structure of SARS-CoV-2 spike protein in complex with double nAbs 8H12 and 1C4 (local refinement)
EMD-35741
Single-particle3.77 Å
Deposition: 26/03/2023Map released: 16/08/2023
Last modified: 13/11/2024
Sample Organism:
Mus musculus,
Severe acute respiratory syndrome coronavirus 2
Sample: Cryo-EM structure of SARS-CoV-2 spike protein in complex with 8H12
Fitted models: 8iv5
Deposition Authors: Sun H
,
Jiang Y,
Zheng Q ,
Li S ,
Xia N
Sample: Cryo-EM structure of SARS-CoV-2 spike protein in complex with 8H12
Fitted models: 8iv5
Deposition Authors: Sun H
,
Jiang Y,
Zheng Q ,
Li S ,
Xia N
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Sun H ,
Deng T,
Zhang Y,
Lin Y,
Jiang Y,
Jiang Y,
Huang Y,
Song S ,
Cui L,
Li T ,
Xiong H,
Lan M,
Liu L,
Li Y,
Fang Q ,
Yu K,
Jiang W,
Zhou L,
Que Y,
Zhang T ,
Yuan Q ,
Cheng T ,
Zhang Z ,
Yu H,
Zhang J ,
Luo W,
Li S ,
Zheng Q ,
Gu Y ,
Xia N
(2024) Protein Cell , 15 , 121 - 134
,
Deng T,
Zhang Y,
Lin Y,
Jiang Y,
Jiang Y,
Huang Y,
Song S ,
Cui L,
Li T ,
Xiong H,
Lan M,
Liu L,
Li Y,
Fang Q ,
Yu K,
Jiang W,
Zhou L,
Que Y,
Zhang T ,
Yuan Q ,
Cheng T ,
Zhang Z ,
Yu H,
Zhang J ,
Luo W,
Li S ,
Zheng Q ,
Gu Y ,
Xia N
(2024) Protein Cell , 15 , 121 - 134
Grant Support: