EMD-35545
Cryo-EM structure of PI3Kalpha in complex with compound 17
EMD-35545
Single-particle3.1 Å
Deposition: 04/03/2023Map released: 13/09/2023
Last modified: 13/09/2023
Sample Organism:
Homo sapiens
Sample: Human PI3Kalpha in complex with compound 17
Fitted models: 8ils
Deposition Authors: Zhou Q
,
Liu X,
Neri D,
Li W,
Favalli N,
Bassi G,
Yang S,
Yang D ,
Vogt PK ,
Wang M-W
Sample: Human PI3Kalpha in complex with compound 17
Fitted models: 8ils
Deposition Authors: Zhou Q
,
Liu X,
Neri D,
Li W,
Favalli N,
Bassi G,
Yang S,
Yang D ,
Vogt PK ,
Wang M-W
Structural insights into the interaction of three Y-shaped ligands with PI3K alpha.
Zhou Q ,
Liu X,
Neri D,
Li W,
Favalli N,
Bassi G,
Yang S,
Yang D ,
Vogt PK ,
Wang MW
(2023) PNAS , 120 , e2304071120 - e2304071120
,
Liu X,
Neri D,
Li W,
Favalli N,
Bassi G,
Yang S,
Yang D ,
Vogt PK ,
Wang MW
(2023) PNAS , 120 , e2304071120 - e2304071120
Grant Support:
- National Natural Science Foundation of China (NSFC): 81872915 (China)
- National Natural Science Foundation of China (NSFC): 82073904 (China)
- National Natural Science Foundation of China (NSFC): 82121005 (China)
- National Natural Science Foundation of China (NSFC): 81973373 (China)
- National Natural Science Foundation of China (NSFC): 21704064 (China)
- Other government: 2018ZX09735-001
- Other government: 2018ZX09711002-002-005
- Other government: 2021ZD0203400
- Other government: 2018YFA0507000
- Other government: ZDKJ2021028
- Other government: NNCAS-2017-1-CC
- National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD): R35 CA197582 (United States)